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Bacterial Resistance to Antimicrobial Agents.

Bacteria AMR

Varela MF, Stephen J, Lekshmi M, Ojha M, Wenzel N, Sanford LM, Hernandez AJ, Parvathi A, 3 and Kumar SH.

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Biggest Threats and Data. 2019 Antimicrobial Resistance Threats Report.

Bacteria AMR

Center for Disease Control and Prevention

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Immunization against poly-N-acetylglucosamine reduces neutrophil activation and GVHD while sparing microbial diversity.

PNAG GVHD Netrophils

Hülsdünker J, Thomas OS, Haring E, Unger S, Gonzalo Núñez N, Tugues S, Gao Z, Duquesne S, Cywes-Bentley C, Oyardi O, Kirschnek S, Schmitt-Graeff A, Pabst O, Koenecke C, Duyster J, Apostolova P, Blaser MJ, Becher B, Pier GB, Häcker G, Zeiser R.

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Antibody to Poly-N-acetyl glucosamine provides protection against intracellular pathogens: Mechanism of action and validation in horse foals challenged with Rhodococcus equi

PNAG Rhodococcus equi

Colette Cywes-Bentley, Joana N. Rocha, Angela I. Bordin, Mariana Vinacur, Safia Rehman ,Tanweer S. Zaidi, Mark Meyer, Sarah Anthony, McKenzie Lambert, Daniel R. Vlock, Steeve Giguère, Noah D. Cohen, Gerald B. Pier

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Structural basis for antibody targeting of the broadly expressed microbial polysaccharide poly-N-acetylglucosamine.

PNAG GVHD Netrophils

Soliman C, Walduck AK, Yuriev E, Richards JS, Cywes-Bentley C, Pier GB, Ramsland PA.

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Extended-spectrum antibodies protective against carbapenemase-producing Enterobacteriaceae.

PNAG Antibody

Skurnik D, Roux D, Pons S, Guillard T, Lu X, Cywes-Bentley C, Pier GB.

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Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogens

PNAG Vaccines

Cywes-Bentley C, Skurnik D, Zaidi T, Roux D, Deoliveira RB, Garrett WS, Lu X, O'Malley J, Kinzel K, Zaidi T, Rey A, Perrin C, Fichorova RN, Kayatani AK, Maira-Litràn T, Gening ML, Tsvetkov YE, Nifantiev NE, Bakaletz LO, Pelton SI, Golenbock DT, Pier

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